SCHEMBL97154

SCHEMBL97154

Cc1ccc(C)c(OC=O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
CYP2C9 P11712 2/20 0.42
HTT P42858 2/20 0.42
LMNA P02545 1/20 0.42
ACHE P22303 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
TDP1 Q9NUW8 3/20 0.39
TTR P02766 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C8 P10632 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA1A P35348 1/20 0.39
PPARG P37231 1/20 0.39
HTR2B P41595 1/20 0.39
PPARA Q07869 1/20 0.39
SLCO1B3 Q9NPD5 1/20 0.39
CISD1 Q9NZ45 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
GAA P10253 1/20 0.39
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28104497 0.96 TSHR (0.46) TSHRCYP2C9HTTLMNAACHE
SCHEMBL14363845 0.84 ACHE (0.48) TSHRCYP2C9HTTLMNAACHE
SCHEMBL16253390 0.84 GAA (0.40) TSHRCYP2C9HTTLMNAACHE
SCHEMBL2089381 0.83 ACHE (0.41) TSHRLMNAACHESMN1; SMN2TDP1
SCHEMBL23457804 0.79 ACHE (0.65) TSHRCYP2C9LMNAACHESMN1; SMN2
SCHEMBL12374357 0.79 TRPA1 (0.46) HTTLMNAACHESMN1; SMN2TDP1
SCHEMBL16574317 0.79 MAOB (0.41) TSHRCYP2C9HTTLMNAACHE
SCHEMBL16022012 0.79 CASP1 (0.47) TSHRHTTLMNASMN1; SMN2GAA
SCHEMBL28342821 0.79 CYP3A4 (0.42) TSHRLMNATDP1HTR2BALDH1A1
SCHEMBL12121021 0.79 ACHE (0.43) CYP2C9HTTLMNAACHESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212163-A1 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2023-07-06 US disclosed
CN-106167473-B 1,4,2- dioxy nitrogen azole compounds and its synthetic method 南开大学 2019-04-05 CN disclosed
US-9856346-B2 Lignin-based biomass epoxy resin, method for manufacturing the same, and compositions including the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-01-02 US disclosed
US-9723769-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-01 US disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-20160102170-A1 LIGNIN-BASED BIOMASS EPOXY RESIN, METHOD FOR MANUFACTURING THE SAME, AND COMPOSITIONS INCLUDING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-04-14 US disclosed
US-9081237-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9057917-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-16 US disclosed
US-20150163968-A1 LIQUID CRYSTAL DISPLAY DEVICE, ALIGNMENT FILM, AND METHODS FOR MANUFACTURING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-06-11 US disclosed
US-9024022-B2 Substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof CIS BIO INTERNATIONAL (FR) 2015-05-05 US disclosed
EP-1678185-A1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-07-12 EP disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
WO-2006035954-A1 CARBOSTYRIL COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-04-06 WO disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
WO-2005042542-A1 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-05-12 WO disclosed
EP-0972758-B1 A process for producing phenolic compounds MITSUBISHI GAS CHEMICAL CO (JP) 2003-01-15 EP disclosed
EP-1209145-A2 Process for preparing an aryl formate and an aromatic carboxylic acid MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-05-29 EP disclosed
US-6187964-B1 FORMING AN ARYL FORMATE AND AROMATIC CARBOXYLIC ACID BY OXIDATION AN AROMATIC ALDEHYDE WITH OXYGEN, SEPARATION A CARBOXYLIC ACID, ARYL FORMATE, UNREACTED ALDEHYDE MIXTURE AND DECOMPOSITION OF FORMATE TO PHENOL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-02-13 US disclosed
EP-0972758-A2 A process for producing phenolic compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-01-19 EP disclosed
US-4259350-A PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK SANKYO COMPANY LIMITED (JP) 1981-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 TSHR 319/4885CYP2C9 2351/4885HTT 4644/4885
US-20230212163-A1 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS EPHX2, CYP8B1, CYP4X1 TSHR 1053/4885CYP2C9 131/4885HTT 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.