Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 12/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917609 | 0.77 | PIN1 (0.52) | PIN1MAPTL3MBTL1 | |
| SCHEMBL16012092 | 0.74 | PIN1 (0.64) | PIN1MAPTALDH1A1 | |
| SCHEMBL8297040 | 0.73 | PIN1 (0.47) | PIN1MAPTALDH1A1 | |
| SCHEMBL30366419 | 0.72 | PIN1 (0.43) | PIN1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL3394316 | 0.71 | PIN1 (0.48) | PIN1 | |
| SCHEMBL16513289 | 0.69 | ABCG2 (0.52) | PIN1MAPTALDH1A1 | |
| SCHEMBL30635859 | 0.69 | ABCG2 (0.52) | PIN1MAPTALDH1A1 | |
| SCHEMBL28787349 | 0.69 | PIN1 (0.46) | PIN1MAPT | |
| SCHEMBL10810225 | 0.69 | MEN1 (0.51) | MAPTPDE10AALDH1A1L3MBTL1NCOA1 | |
| SCHEMBL13166210 | 0.68 | ABCG2 (0.51) | PIN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014135244-A1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF DISEASES SUCH AS CANCER | MERCK PATENT GMBH (DE) | 2014-09-12 | — | — | WO | disclosed |