Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 15/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16140986 | 0.88 | PIN1 (0.46) | PIN1 | |
| SCHEMBL10098687 | 0.85 | PIN1 (0.43) | PIN1KDM4EMAPTTSHR | |
| SCHEMBL29904737 | 0.77 | PIN1 (0.44) | PIN1KDM4EMAPT | |
| SCHEMBL26907039 | 0.77 | PIN1 (0.44) | PIN1KDM4EMAPT | |
| SCHEMBL21937971 | 0.76 | PIN1 (0.39) | PIN1KDM4EMAPT | |
| SCHEMBL1917609 | 0.76 | PIN1 (0.52) | PIN1MAPT | |
| SCHEMBL28662304 | 0.76 | PIN1 (0.42) | PIN1MAPT | |
| SCHEMBL29152338 | 0.75 | PIN1 (0.45) | PIN1MAPT | |
| SCHEMBL19436599 | 0.75 | ALDH1A1 (0.40) | PIN1KDM4EMAPT | |
| SCHEMBL8297040 | 0.74 | PIN1 (0.47) | PIN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375713-A | DCLK1 protein degradation targeting chimeric and application thereof | 中国人民解放军海军军医大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-114478539-A | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2022-05-13 | — | — | CN | disclosed |