Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16014680 | 0.81 | ALDH1A1 (0.52) | ALDH1A1APLNRSMN1; SMN2HTTCMA1 | |
| SCHEMBL16014406 | 0.79 | MAPT (0.46) | ALDH1A1APLNRSMN1; SMN2HTTCMA1 | |
| SCHEMBL17403441 | 0.77 | ACP1 (0.44) | ALDH1A1SMN1; SMN2ADORA2AMEN1KMT2A | |
| SCHEMBL16023894 | 0.75 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2NPBWR1ADORA2AMAPT | |
| SCHEMBL18723727 | 0.70 | PIK3CA (0.43) | ALDH1A1APLNRSMN1; SMN2HTTCMA1 | |
| SCHEMBL15556570 | 0.69 | ALDH1A1 (0.44) | ALDH1A1APLNRCMA1NPBWR1ADORA2A | |
| SCHEMBL15556088 | 0.69 | MAPT (0.40) | ALDH1A1APLNRSMN1; SMN2HTTCMA1 | |
| SCHEMBL15606508 | 0.68 | PIK3CA (0.43) | ALDH1A1APLNRSMN1; SMN2HTTCMA1 | |
| SCHEMBL15556714 | 0.68 | MAPT (0.47) | APLNRSMN1; SMN2CMA1NPBWR1MAPT | |
| SCHEMBL16014845 | 0.66 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTTCMA1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014135472-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-09-12 | — | — | WO | disclosed |