Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | BUB1 | O43683 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17366562 | 0.90 | ACP1 (0.42) | ACP1KCNH3ALDH1A1MAPTLMNA | |
| SCHEMBL16023894 | 0.87 | SMN1; SMN2 (0.38) | ACP1ALDH1A1MAPTADORA2ASMN1; SMN2 | |
| SCHEMBL17366559 | 0.80 | ALDH1A1 (0.49) | KCNH3ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL15555010 | 0.78 | ACHE (0.43) | LMNAHDAC6MEN1NPC1RAB9A | |
| SCHEMBL16014413 | 0.78 | AR (0.44) | BUB1PTK2IGF1RMAPK1 | |
| SCHEMBL16014680 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAALOX15NPSR1 | |
| SCHEMBL16023965 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTADORA2ASMN1; SMN2MEN1 | |
| SCHEMBL15556306 | 0.77 | MEN1 (0.46) | ACP1MAPTLMNAHPGDHSD17B10 | |
| SCHEMBL15606470 | 0.77 | NPBWR1 (0.39) | ACP1KCNH3MAPTLMNAJAK2 | |
| SCHEMBL15904396 | 0.76 | AKR1C3 (0.41) | ACP1ALDH1A1BUB1ADORA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002180-A1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002180-A1 | ANTIVIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | ACP1 4504/4885KCNH3 4411/4885ALDH1A1 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.