Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15806698 | 0.91 | SIGMAR1 (0.50) | SIGMAR1BCHEMAOACHRM2S1PR1 | |
| SCHEMBL16024318 | 0.87 | SIGMAR1 (0.46) | SIGMAR1BCHES1PR1S1PR3S1PR2 | |
| SCHEMBL16024317 | 0.86 | SIGMAR1 (0.45) | SIGMAR1BCHES1PR1S1PR3S1PR5 | |
| SCHEMBL16024330 | 0.86 | SIGMAR1 (0.45) | SIGMAR1BCHES1PR1S1PR3S1PR5 | |
| SCHEMBL16026199 | 0.86 | SIGMAR1 (0.45) | SIGMAR1BCHES1PR1S1PR3S1PR2 | |
| SCHEMBL16024322 | 0.86 | SIGMAR1 (0.46) | SIGMAR1BCHES1PR1S1PR3HDAC3 | |
| SCHEMBL16026090 | 0.86 | HDAC1 (0.44) | SIGMAR1BCHES1PR1S1PR3S1PR2 | |
| SCHEMBL13469983 | 0.85 | SIGMAR1 (0.46) | SIGMAR1S1PR1S1PR3S1PR2S1PR5 | |
| SCHEMBL28784998 | 0.84 | MAPT (0.50) | SIGMAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27522937 | 0.84 | MAPT (0.50) | SIGMAR1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014138075-A1 | PHOSPHONIC ACID COMPOUNDS AS SPHINGOSINE-1-PHOSPHATE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-09-12 | — | — | WO | disclosed |
| US-20140256945-A1 | PHOSPHONIC ACID COMPOUNDS AS SPHINGOSINE-1-PHOSPHATE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256945-A1 | PHOSPHONIC ACID COMPOUNDS AS SPHINGOSINE-1-PHOSPHATE RECEPTOR MODULATORS | S1PR1, S1PR2, S1PR5 | SIGMAR1 341/4885BCHE 4082/4885MAOA 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.