Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16024302 | 0.90 | MCHR1 (0.41) | HDAC1S1PR1S1PR3S1PR5S1PR2 | |
| SCHEMBL15806670 | 0.88 | PLA2G4B (0.41) | HDAC1SIGMAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL16024316 | 0.86 | SIGMAR1 (0.60) | HDAC1SIGMAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL16024289 | 0.83 | SIGMAR1 (0.39) | HDAC1SIGMAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL16024308 | 0.83 | KDM4E (0.40) | HDAC1SIGMAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL16024333 | 0.81 | KDM4E (0.43) | HDAC1SIGMAR1BCHE | |
| SCHEMBL16026224 | 0.81 | KDM4E (0.43) | SIGMAR1BCHE | |
| SCHEMBL15807177 | 0.80 | HDAC1 (0.36) | HDAC1SIGMAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL15806656 | 0.80 | HDAC1 (0.34) | HDAC1S1PR1 | |
| SCHEMBL16010954 | 0.79 | S1PR3 (0.67) | HDAC1SIGMAR1S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256945-A1 | PHOSPHONIC ACID COMPOUNDS AS SPHINGOSINE-1-PHOSPHATE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256945-A1 | PHOSPHONIC ACID COMPOUNDS AS SPHINGOSINE-1-PHOSPHATE RECEPTOR MODULATORS | S1PR1, S1PR2, S1PR5 | HDAC1 2571/4885SIGMAR1 341/4885S1PR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.