Aniline

Aniline

SCHEMBL160252

Nc1ccccc1.c1cnc2cnnnc2c1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.38
MAPT P10636 4/20 0.37
ATM Q13315 2/20 0.37
HSP90AA1 P07900 2/20 0.37
HSP90AB1 P08238 2/20 0.37
HTT P42858 2/20 0.37
KDM4E B2RXH2 2/20 0.37
TP53 P04637 1/20 0.37
CASP1 P29466 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NCF1 P14598 1/20 0.35
CYP3A4 P08684 1/20 0.34
NPC1 O15118 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
RAB9A P51151 3/20 0.34
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162279 0.87 ALDH1A1 (0.44) ALDH1A1TSHRMAPTATMHSP90AA1
SCHEMBL29389802 0.87 ALDH1A1 (0.44) ALDH1A1TSHRMAPTATMHSP90AA1
Quinoxaline SCHEMBL11662642 0.72 TSHR (0.58) ALDH1A1TSHRMAPTATMHSP90AA1
Quinoline SCHEMBL27592016 0.72 ALDH1A1 (0.71) ALDH1A1TSHRMAPTATMHSP90AA1
Quinoline SCHEMBL28081711 0.71 ALDH1A1 (0.63) ALDH1A1TSHRMAPTATMHSP90AA1
Aniline SCHEMBL2858457 0.68 NCF1 (0.66) ALDH1A1TSHRMAPTHSP90AA1HSP90AB1
Quinoline SCHEMBL27921696 0.68 ALDH1A1 (0.63) ALDH1A1TSHRMAPTATMHSP90AA1
Aniline SCHEMBL28466027 0.66 HSP90AA1 (0.67) ALDH1A1TSHRMAPTHSP90AA1KDM4E
Aniline SCHEMBL6725167 0.66 TSHR (0.61) ALDH1A1TSHRMAPTHTTKDM4E
Aniline SCHEMBL3069791 0.66 TSHR (0.61) ALDH1A1TSHRMAPTHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3372672-A1 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS Janssen Biotech, Inc. (US) 2018-09-12 EP claimed
CN-102159703-B Differentiation of Pluripotent Stem Cells CENTOCOR ORTHO BIOTECH INC. (US) 2015-11-25 CN claimed
EP-2310492-B1 DIFFERENTIATION OF PLURIPOTENT STEM CELLS JANSSEN BIOTECH INC (US) 2015-07-22 EP claimed
EP-2853589-A1 Differentiation of human embryonic stem cells Janssen Biotech, Inc. (US) 2015-04-01 EP claimed
CN-103221536-A Differentiation of human embryonic stem cells JANSSEN BIOTECH INC 2013-07-24 CN claimed
EP-2611909-A2 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS Janssen Biotech, Inc. (US) 2013-07-10 EP claimed
EP-2611910-A2 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS Janssen Biotech, Inc. (US) 2013-07-10 EP claimed
CN-103154239-A Differentiation of human embryonic stem cells JANSSEN BIOTECH INC 2013-06-12 CN claimed
US-20120190111-A1 Differentiation of Pluripotent Stem Cells CENTOCOR ORTHO BIOTECH INC. 2012-07-26 US claimed
WO-2012030539-A2 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS JANSSEN BIOTECH, INC. (US) 2012-03-08 WO claimed
WO-2012030538-A2 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS JANSSEN BIOTECH, INC. (US) 2012-03-08 WO claimed
US-20120052571-A1 Differentiation of Human Embryonic Stem Cells JANSSEN BIOTECH, INC. (US) 2012-03-01 US claimed
US-20120052575-A1 Differentiation of Human Embryonic Stem Cells JANSSEN BIOTECH, INC. (US) 2012-03-01 US claimed
JP-2011526786-A 2011-10-20 JP claimed
CN-102159703-A Differentiation of pluripotent stem cells CENTOCOR ORTHO BIOTECH INC 2011-08-17 CN claimed
EP-2310492-A1 DIFFERENTIATION OF PLURIPOTENT STEM CELLS Centocor Ortho Biotech Inc. (US) 2011-04-20 EP claimed
US-20100015711-A1 Differentiation of Pluripotent Stem Cells JANSSEN BIOTECH, INC. 2010-01-21 US claimed
WO-2010002846-A1 DIFFERENTIATION OF PLURIPOTENT STEM CELLS CENTOCOR ORTHO BIOTECH INC. (US) 2010-01-07 WO claimed
CN-108517310-B Differentiation of human embryonic stem cells 詹森生物科技公司 2022-02-15 CN disclosed
WO-2010002846-A1 DIFFERENTIATION OF PLURIPOTENT STEM CELLS CENTOCOR ORTHO BIOTECH INC. (US) 2010-01-07 WO disclosed