SCHEMBL1603039

SCHEMBL1603039

C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)C=C4)[nH]3.[As]

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29430977 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL15809 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL6517023 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL30821407 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL6744970 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL9430673 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL1572838 0.95 STAT3 (0.41) STAT3STAT1
SCHEMBL5069984 0.95 STAT3 (0.41) STAT3STAT1
SCHEMBL705768 0.95 STAT3 (0.41) STAT3STAT1
Bromide SCHEMBL11339396 0.95 STAT3 (0.41) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078220-B2 High-purity large-scale preparation of stannsoporfin Mallinckrodt Hospital Products IP Limited (IE) 2021-08-03 — — US disclosed
US-20200255458-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN MALLINCKRODT LLC 2020-08-13 — — US disclosed
US-10662209-B2 High-purity large-scale preparation of stannsoporfin Mallinckrodt Hospital Products IP Limited (IE) 2020-05-26 — — US disclosed
US-20190202846-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SpecGx LLC 2019-07-04 — — US disclosed
US-10273255-B2 High-purity large-scale preparation of stannsoporfin INFACARE PHARMACEUTICAL CORPORATION (US) 2019-04-30 — — US disclosed
CN-104116745-B composition comprising stannsoporfin 婴儿护理药品公司 2018-07-06 — — CN disclosed
US-20180134735-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN MALLINCKRODT LLC 2018-05-17 — — US disclosed
US-9902745-B2 High-purity large-scale preparation of stannsoporfin INFACARE PHARMACEUTICAL CORPORATION (US) 2018-02-27 — — US disclosed
US-20170073362-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN VTESSE LLC 2017-03-16 — — US disclosed
US-9517239-B2 High-purity large-scale preparation of stannsoporfin INFACARE PHARMACEUTICAL CORPORATION (US) 2016-12-13 — — US disclosed
US-8835416-B2 High-purity large-scale preparation of stannsoporfin INFACARE PHARMACEUTICAL CORPORATION (US) 2014-09-16 — — US disclosed
US-20140005380-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN INFACARE PHARMACEUTICAL CORPORATION (US) 2014-01-02 — — US disclosed
US-8530458-B2 High-purity large-scale preparation of stannsoporfin INFACARE PHARMACEUTICAL CORPORATION (US) 2013-09-10 — — US disclosed
EP-2384756-A2 High-purity large-scale preparation of stannsoporfin InfaCare Pharmaceutical Corporation (US) 2011-11-09 — — EP disclosed
US-7960371-B2 reduction of hemin with hydrogenation catalysts, in the presence of hydrogen, then heating to remove iron and form mesoporphyrin, and reacting with tin oxide top form pure tin mesoporphyrin; inhibitor of heme oxygenase, used in the treatment of infant jaundice or hyperbilirubinemia; liver disorders INFACARE PHARMACEUTICAL CORPORATION (US) 2011-06-14 — — US disclosed
US-20110082292-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN OCERA THERAPEUTICS LLC 2011-04-07 — — US disclosed
CN-101573122-A High purity large scale preparation of stannsoporfin INFACARE PHARMACEUTICAL CORP (US) 2009-11-04 — — CN disclosed
EP-2079472-A2 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN InfaCare Pharmaceutical Corporation (US) 2009-07-22 — — EP disclosed
US-20080125585-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN STRATATECH CORPORATION 2008-05-29 — — US disclosed
WO-2008045377-A2 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN INFACARE PHARMACEUTICAL CORPORATION (US) 2008-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140005380-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-20180134735-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-10662209-B2 High-purity large-scale preparation of stannsoporfin SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-20080125585-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-10273255-B2 High-purity large-scale preparation of stannsoporfin SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-20200255458-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-20170073362-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-11078220-B2 High-purity large-scale preparation of stannsoporfin SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-20190202846-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885
US-20110082292-A1 HIGH-PURITY LARGE-SCALE PREPARATION OF STANNSOPORFIN SNRPF, HNRNPF, NUP188 STAT3 4852/4885STAT1 4523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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