SCHEMBL1572838

SCHEMBL1572838

C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)C=C4)[nH]3.[Au]

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9430673 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL6517023 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL30821407 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL29430977 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL6744970 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL15809 0.97 STAT3 (0.42) STAT3STAT1
SCHEMBL21729 0.95 STAT3 (0.41) STAT3STAT1
SCHEMBL705768 0.95 STAT3 (0.41) STAT3STAT1
SCHEMBL9717057 0.95 STAT3 (0.41) STAT3STAT1
SCHEMBL1603039 0.95 STAT3 (0.41) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4635517-A1 METAL-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THEREOF Laboratory for Synthetic Chemistry and Chemical Biology Limited (HK) 2025-10-22 — — EP claimed
CN-119504769-A Antibody-coupled gold (III) porphyrin medicine targeting HER2, synthesis and tumor treatment application thereof 高博药业有限公司 2025-02-25 — — CN claimed
CN-116689030-A MB@Apt-COF composite material and preparation method and application thereof 河北科技大学 2023-09-05 — — CN claimed
CN-108779124-B Gold porphyrin-PEG conjugates and methods of use 香港大学 2022-03-01 — — CN claimed
CN-105597098-B A kind of bonded gold nanorods compound of Herceptin, preparation method and the application in HER2 positive breast cancer diagnosis and treatment 哈尔滨医科大学 2019-05-31 — — CN claimed
CN-109464986-A A kind of preparation and application of the nanocomposite based on porphyrin metal organic frame and ternary sulfide 西北师范大学 2019-03-15 — — CN claimed
CN-107064277-B A kind of preparation method and application of electrochemical sensor 湖北民族学院 2018-03-20 — — CN claimed
CN-107064277-A A kind of preparation method and application of electrochemical sensor 湖北民族学院 2017-08-18 — — CN claimed
CN-105597098-A Trastuzumab bond-linking gold nanorod compound, preparation method and application thereof in diagnosis and treatment of HER2 positive breast cancer UNIV HARBIN MEDICAL 2016-05-25 — — CN claimed
CN-102167704-B Water-soluble porphyrin gold (III) anticancer compounds and preparation method thereof UNIV YANGZHOU 2014-05-14 — — CN claimed
CN-102268003-B Unsymmetrical poly-substituted porphyrin gold (III) type anticancer compound and preparation method thereof UNIV YANGZHOU 2013-10-30 — — CN claimed
CN-102180883-B Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof UNIV YANGZHOU 2013-04-17 — — CN claimed
CN-102268003-A Unsymmetrical poly-substituted porphyrin gold (III) type anticancer compound and preparation method thereof — 2011-12-07 — — CN claimed
CN-102180883-A Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof UNIV YANGZHOU 2011-09-14 — — CN claimed
CN-102167704-A Water-soluble porphyrin gold (III) anticancer compounds and preparation method thereof UNIV YANGZHOU 2011-08-31 — — CN claimed
US-6727358-B2 NONLINEAR OPTICAL OR ELECTRICAL RESPONSE NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) 2004-04-27 — — US claimed
US-20030187251-A1 Porphyrin array having imidazolyl porphyrin metal complex as structural unit thereof and method of producing the same NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) 2003-10-02 — — US claimed
EP-4635517-A1 METAL-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THEREOF Laboratory for Synthetic Chemistry and Chemical Biology Limited (HK) 2025-10-22 — — EP disclosed
WO-2004024146-A1 METHODS FOR USING GOLD (III) COMPLEXES AS ANTI-TUMOR AND ANTI-HIV AGENTS THE UNIVERSITY OF HONG KONG (CN) 2004-03-25 — — WO disclosed
US-20030187251-A1 Porphyrin array having imidazolyl porphyrin metal complex as structural unit thereof and method of producing the same NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) 2003-10-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187251-A1 Porphyrin array having imidazolyl porphyrin metal complex as structural unit thereof and method of producing the same MT-CO1, CYC1, AP1M1 STAT3 2712/4885STAT1 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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