SCHEMBL1604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Bicarbonate SCHEMBL18167212	0.81	NPC1 (0.39)	RAB9ASMN1; SMN2TP53TSHRALDH1A1
	SCHEMBL3680	0.80	LPAR1 (0.49)	SMN1; SMN2TSHRALDH1A1NR1H4MAPT
	SCHEMBL1702	0.76	KCNA3 (0.45)	RAB9ALMNAALDH1A1LPAR1KMT2A
	SCHEMBL6838	0.72	L3MBTL1 (0.40)	L3MBTL1RAB9ASMN1; SMN2LMNATP53
	SCHEMBL1165	0.72	KMT2A (0.45)	SMN1; SMN2ALDH1A1CYP1A2MAPTPOLB
	SCHEMBL18597729	0.72	HSP90AA1 (0.38)	L3MBTL1RAB9ASMN1; SMN2LMNATP53
	SCHEMBL6841	0.72	CYP1A2 (0.38)	L3MBTL1RAB9ASMN1; SMN2LMNATP53
	SCHEMBL4402	0.71	L3MBTL1 (0.41)	L3MBTL1RAB9ASMN1; SMN2LMNATSHR
	SCHEMBL1475	0.71	L3MBTL1 (0.45)	L3MBTL1RAB9ASMN1; SMN2LMNATSHR
	SCHEMBL1463	0.71	TSHR (0.47)	L3MBTL1RAB9ASMN1; SMN2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.