Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10301709 | 0.81 | — | — | |
| SCHEMBL6061169 | 0.76 | STAT3 (0.33) | PPM1D | |
| SCHEMBL4195541 | 0.76 | STAT3 (0.33) | PPM1D | |
| SCHEMBL2689416 | 0.72 | STAT3 (0.33) | PPM1D | |
| SCHEMBL13759526 | 0.71 | STAT3 (0.31) | PPM1D | |
| SCHEMBL1604047 | 0.69 | — | — | |
| SCHEMBL9973227 | 0.69 | STAT3 (0.39) | PPM1D | |
| SCHEMBL26323710 | 0.68 | PPM1D (0.44) | PPM1D | |
| SCHEMBL3186681 | 0.68 | PPM1D (0.44) | PPM1D | |
| SCHEMBL14389714 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217023-B2 | 19-nor-vitamin D analogs with 1,2- or 3,2-cyclopentene ring | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110082122-A1 | 19-Nor-Vitamin D Analogs With 1,2- or 3,2-Cyclopentene Ring | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082122-A1 | 19-Nor-Vitamin D Analogs With 1,2- or 3,2-Cyclopentene Ring | CYP24A1, CYP2R1, CYP27B1 | PPM1D 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.