SCHEMBL160454

SCHEMBL160454

CCCC[CH]c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.40
CYP2A6 P11509 1/20 0.40
EGFR P00533 1/20 0.39
HDAC3 O15379 1/20 0.39
CNR1 P21554 1/20 0.39
LTA4H P09960 2/20 0.38
PCSK9 Q8NBP7 1/20 0.38
PTGS2 P35354 1/20 0.36
RELA Q04206 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38728 0.93 LMNA (0.46) LMNATDP1ALDH1A1CYP2A6EGFR
SCHEMBL139446 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL5206775 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL2125298 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL302971 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL303521 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL304116 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL303164 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL302694 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2
SCHEMBL302928 0.91 TDP1 (0.47) LMNATDP1EGFRCNR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6309 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118275563-A Method for detecting migration quantity of PGA oligomer in food packaging material 中国神华煤制油化工有限公司 2024-07-02 CN claimed
US-20240188441-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS AND ELECTRONIC DEVICE INCLUDING THE LIGHT-EMITTING DEVICE, AND THE CONDENSED CYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-06 US claimed
WO-2024104384-A1 INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS NUCMITO PHARMACEUTICALS CO. LTD. (CN) 2024-05-23 WO claimed
CN-115838368-B Hydroxamic acid compound and derivative thereof, preparation method, pharmaceutical composition and application 中国药科大学 2024-02-27 CN claimed
CN-114230528-B Method for preparing quinoxalinone derivative 桂林理工大学 2024-02-06 CN claimed
CN-117164492-A Organic semiconductor g-C 3 N 4 Method for catalytic synthesis of (E) -vinyl selenone compound 化学与精细化工广东省实验室 2023-12-05 CN claimed
WO-2023227472-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2023-11-30 WO claimed
CN-116903480-A Method for preparing beta-enaminone based on sulfoxide and aldoxime and beta-enaminone 盐城师范学院 2023-10-20 CN claimed
EP-4259711-A1 ADDITIVE MIXTURES BASF SE (DE) 2023-10-18 EP claimed
EP-4259710-A1 AN ORGANIC MATERIAL BASED SHAPED ARTICLE BASF SE (DE) 2023-10-18 EP claimed
EP-0199543-A2 Heterocyclic amide derivatives ICI AMERICAS INC. (US) 1986-10-29 EP claimed
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP claimed
EP-0179615-A2 A housing seal XEROX CORPORATION (US) 1986-04-30 EP claimed
EP-0071613-B1 ACRYLIC COATING COMPOSITIONS DULUX AUSTRALIA LTD (AU) 1986-04-23 EP claimed
EP-0027620-B1 2,2,6,6-TETRAALKYL-4-PIPERIDYL-BIS-SPIRO-ETHERS AND SYNTHETIC POLYMERS STABILISED THEREWITH ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-07-24 EP claimed
EP-0138481-A2 Leukotriene biosynthesis inhibitors MERCK FROSST CANADA INC. (CA) 1985-04-24 EP claimed
EP-0010317-B1 6-, 1- AND 2-SUBSTITUTED-1-CARBAPEN-2-EM-3-CARBOXYLIC ACIDS, PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITION COMPRISING SUCH COMPOUNDS MERCK & CO. INC. (US) 1983-12-21 EP claimed
US-4410730-A Process for the production of o-(N-monosubstituted amino)benzyl alcohols SHIONOGI & CO., LTD. (JP) 1983-10-18 US claimed
US-4399147-A Prostaglandin 12 analogues and their pharmaceutical compositions ONO PHARMACEUTICAL CO. LTD. (JP) 1983-08-16 US claimed
US-4341706-A Process for the preparation of carbapenem antibiotics MERCK & CO., INC. (US) 1982-07-27 US claimed