SCHEMBL16047045

SCHEMBL16047045

CCCCCCCCCCCCCCCCCC[Si](Cl)(Cl)C[Si](Cl)(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 3/20 0.38
DNM1 Q05193 6/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16047303 1.00 TSHR (0.40) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL9080417 0.90 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL134147 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL135669 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL14645782 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL132353 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL2763894 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11313336 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL21817819 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL131055 0.84 TSHR (0.50) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4717462-A1 INK-REPELLENT MEMBER, METHOD OF PRODUCING INK-REPELLENT MEMBER, INK JET HEAD, AND METHOD OF PRODUCING ARTICLE Canon Kabushiki Kaisha (JP) 2026-04-01 EP disclosed
US-20260085195-A1 INK-REPELLENT MEMBER, METHOD OF PRODUCING INK-REPELLENT MEMBER, INK JET HEAD, AND METHOD OF PRODUCING ARTICLE CANON KK (JP) 2026-03-26 US disclosed
US-8921579-B2 Pendant dipodal silanes having a disilapropyl terminus GELEST TECHNOLOGIES, INC. (US) 2014-12-30 US disclosed
US-20140275574-A1 PENDANT DIPODAL SILANES HAVING A DISILAPROPYL TERMINUS GELEST TECHNOLOGIES, INC. (US) 2014-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085195-A1 INK-REPELLENT MEMBER, METHOD OF PRODUCING INK-REPELLENT MEMBER, INK JET HEAD, AND METHOD OF PRODUCING ARTICLE DOT1L, H1-0, H1-3 TSHR 1762/4885THRB 2928/4885ALDH1A1 2434/4885
US-20140275574-A1 PENDANT DIPODAL SILANES HAVING A DISILAPROPYL TERMINUS RBX1, DDX3X, PRXL2A TSHR 4801/4885THRB 4635/4885ALDH1A1 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.