Benzoyl Formic Acid

Benzoyl Formic Acid

SCHEMBL16047239

CC(C)CC(O)C(C)C(C)O.O=C(O)C(=O)c1ccccc1.O=C(O)c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoyl Formic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 8/20 0.44
CES2 O00748 7/20 0.44
DAO P14920 1/20 0.41
TSHR P16473 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
MAPT P10636 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 3/20 0.40
ALDH1A1 P00352 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 2/20 0.40
NPSR1 Q6W5P4 2/20 0.39
XBP1 P17861 1/20 0.39
ATM Q13315 1/20 0.39
SRD5A2 P31213 1/20 0.37
KDM4E B2RXH2 2/20 0.36
FOLH1 Q04609 1/20 0.35
MAPK1 P28482 2/20 0.35
PTPN1 P18031 2/20 0.35
PTPRC P08575 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL1785967 0.92 TSHR (0.48) CES1CES2DAOTSHRNAPRT
Benzoyl Formic Acid SCHEMBL16045929 0.86 CES2 (0.55) CES1CES2DAOTSHRNAPRT
Benzoic Acid SCHEMBL16047909 0.85 NPSR1 (0.36) CES1CES2DAOTSHRNAPRT
Benzoic Acid SCHEMBL29415289 0.83 DAO (0.39) CES1CES2DAOTSHRNAPRT
Benzoic Acid SCHEMBL4837055 0.82 TSHR (0.52) CES1CES2DAOTSHRNAPRT
Benzoyl Formic Acid SCHEMBL16045776 0.82 CES2 (0.59) CES1CES2DAOTSHRNAPRT
Benzoic Acid SCHEMBL16045122 0.82 ALDH1A1 (0.40) CES1CES2DAOTSHRNAPRT
Benzoic Acid SCHEMBL16045788 0.82 TSHR (0.43) CES1CES2DAOTSHRNAPRT
Benzoyl Formic Acid SCHEMBL16044287 0.82 CES1 (0.41) CES1CES2DAOTSHRNAPRT
Benzoyl Formic Acid SCHEMBL16044060 0.81 CES2 (0.50) CES1CES2DAOTSHRNAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN claimed
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
CN-109180843-B Non-phthalate compounds as electron donors for polyolefin catalysts 美国台塑公司 2022-03-01 CN disclosed
US-9790291-B2 Non-phthalate compounds as electron donors for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-17 US disclosed
EP-2969201-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS Formosa Plastics Corporation, U.S.A. (US) 2016-01-20 EP disclosed
WO-2014160012-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-10-02 WO disclosed
US-20140275456-A1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-09-18 US disclosed