SCHEMBL16047366

SCHEMBL16047366

CC(C)C(OS(=O)(=O)c1ccccc1)C(C)(C)COS(=O)(=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARL Q9H300 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ATM Q13315 2/20 0.33
HSD11B1 P28845 1/20 0.33
PSIP1 O75475 1/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HSP90AA1 P07900 1/20 0.33
XBP1 P17861 1/20 0.33
MPI P34949 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MCL1 Q07820 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ADAMTS4 O75173 1/20 0.32
GLA P06280 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14779894 0.82 ALDH1A1 (0.40) PARLALDH1A1HSD11B1PSIP1MAPT
SCHEMBL16045751 0.81 KMT2A (0.43) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL16045753 0.81 MAPK1 (0.47) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL14779810 0.78 ALDH1A1 (0.39) PARLALDH1A1HSD11B1PSIP1MAPT
SCHEMBL3447252 0.77 PSIP1 (0.45) PARLALDH1A1ATMHSD11B1PSIP1
SCHEMBL14778596 0.76 PSIP1 (0.39) ALDH1A1ATMHSD11B1PSIP1MAPT
SCHEMBL5590961 0.76 PSIP1 (0.43) PARLALDH1A1ATMHSD11B1PSIP1
SCHEMBL2057595 0.76 PSIP1 (0.43) PARLALDH1A1ATMHSD11B1PSIP1
SCHEMBL14779499 0.74 ALDH1A1 (0.41) PARLALDH1A1HSD11B1PSIP1MAPT
SCHEMBL16045861 0.74 PSIP1 (0.40) PARLALDH1A1ATMHSD11B1PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
US-9790291-B2 Non-phthalate compounds as electron donors for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-17 US disclosed
EP-2969201-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS Formosa Plastics Corporation, U.S.A. (US) 2016-01-20 EP disclosed
WO-2014160012-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-10-02 WO disclosed
US-20140275456-A1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-09-18 US disclosed