Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | DAO | P14920 | 1/20 | 1.00 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 1.00 |
| ▸ | CES2 | O00748 | 3/20 | 0.78 |
| ▸ | CES1 | P23141 | 3/20 | 0.78 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA6 | P23280 | 2/20 | 0.58 |
| ▸ | CA5A | P35218 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL4591761 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL149318 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9751726 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL407365 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL137419 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL975929 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11602198 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3966600 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL976149 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7719037 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 481 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025238576-A1 | SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION | Nuovo Pignone Tecnologie – S.r.l. (IT) | 2025-11-20 | — | — | WO | claimed |
| US-20250354659-A1 | SYSTEM AND METHOD FOR STORING LIQUIDS HAVING LOW LATENT HEAT OF VAPORIZATION | NUOVO PIGNONE TECNOLOGIE – S R L (IT) | 2025-11-20 | — | — | US | claimed |
| US-12397489-B2 | Methods of making metal-organic framework extrudates | ExxonMobil Technology and Engineering Company (US) | 2025-08-26 | — | — | US | claimed |
| EP-4598672-A1 | HYBRID ADSORBENT GRANULES AND FILTERS MADE WITH THE GRANULES | Numat Technologies Inc. (US) | 2025-08-13 | — | — | EP | claimed |
| US-20250106549-A1 | AIR ADSORBENTS FOR MICRO SPEAKER INCLUDING HYDROPHOBIC METAL-ORGANIC FRAMEWORK AND SPEAKER BOX SYSTEM INCLUDING THE SAME | NEXVEL CO., LTD (KR) | 2025-03-27 | — | — | US | claimed |
| EP-4526587-A2 | LIQUEFIED GAS SYSTEM WITH BOIL-OFF CAPTURE | Numat Technologies Inc. (US) | 2025-03-26 | — | — | EP | claimed |
| US-20240261758-A1 | Spherical Metal-Organic Frameworks Using Alginate | ExxonMobil Technology and Engineering Company | 2024-08-08 | — | — | US | claimed |
| US-20240247002-A1 | Flocculation and Rapid Filtration Of Metal Organic Frameworks | ExxonMobil Technology and Engineering Company | 2024-07-25 | — | — | US | claimed |
| WO-2024107531-A1 | HYBRID ADSORBENT GRANULES AND FILTERS MADE WITH THE GRANULES | NUMAT TECHNOLOGIES, INC (US) | 2024-05-23 | — | — | WO | claimed |
| CN-113474923-B | Anode binder for lithium rechargeable battery, anode binder comprising cured product of the anode binder | 株式会社LG化学 | 2024-04-26 | — | — | CN | claimed |
| EP-1770121-B1 | Pneumatic tire having a rubber component containing zinc organic framework material | GOODYEAR TIRE & RUBBER (US) | 2008-10-01 | — | — | EP | claimed |
| US-20080045678-A1 | Pneumatic tire | GOODYEAR TIRE & RUBBER COMPANY, THE | 2008-02-21 | — | — | US | claimed |
| EP-1770121-A1 | Pneumatic tire having a rubber component containing zinc organic framework material | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-04-04 | — | — | EP | claimed |
| US-20070062625-A1 | Pneumatic tire having a rubber component containing zinc organic framework material | KOSTER GEORGES | 2007-03-22 | — | — | US | claimed |
| US-7179765-B2 | Process for preparing hydrogen peroxide from the elements | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-20 | — | — | US | claimed |
| US-20060057057-A1 | Process for preparing hydrogen peroxide from the elements | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-16 | — | — | US | claimed |
| US-7008607-B2 | Process for preparing hydrogen peroxide from the elements | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-07 | — | — | US | claimed |
| US-20040081611-A1 | Process for preparing hydrogen peroxide from the elements | BASF AKIENGESELLSCHAFT (DE) | 2004-04-29 | — | — | US | claimed |
| US-6624318-B1 | Process for the epoxidation of an organic compound with oxygen or an oxygen-delivering compounds using catalysts containing metal-organic frame-work materials | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | claimed |
| US-6617467-B1 | Polymerizing carbon dioxide with an alkylene oxide in the presence of a catalytic framework material comprising pores and a metal ion with a bidentate organic compound coordinated to the ion | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240247002-A1 | Flocculation and Rapid Filtration Of Metal Organic Frameworks | FLOT1, HNRNPF, POF1B | TSHR 2095/4885DAO 4017/4885NAPRT 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.