Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691384 | 0.76 | BRD4 (0.45) | MEN1KMT2ABRD4TSHROPRM1 | |
| SCHEMBL24148135 | 0.71 | MEN1 (0.57) | MEN1KMT2AALDH1A1TSHROPRM1 | |
| SCHEMBL7341973 | 0.71 | PDE3B (0.53) | — | |
| SCHEMBL7341554 | 0.69 | CYP1A2 (0.35) | KMT2ABRD4ALDH1A1LMNACYP1A2 | |
| SCHEMBL29704482 | 0.68 | MEN1 (0.47) | MEN1KMT2ABRD4ALDH1A1TSHR | |
| SCHEMBL19644092 | 0.68 | MEN1 (0.47) | MEN1KMT2ABRD4ALDH1A1TSHR | |
| SCHEMBL10694040 | 0.63 | HPGD (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31426217 | 0.62 | PBRM1 (0.58) | PBRM1MEN1KMT2AAHRALDH1A1 | |
| SCHEMBL29891547 | 0.62 | PGR (0.53) | BRD4ALDH1A1LMNAPOLB | |
| SCHEMBL3519770 | 0.62 | PGR (0.53) | BRD4ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014143617-A1 | DEUTERIUM-ENRICHED TANAPROGET AND PROCESSES FOR ITS PREPARATION | TEVA WOMEN'S HEALTH, INC. (US) | 2014-09-18 | — | — | WO | claimed |
| WO-2014143617-A1 | DEUTERIUM-ENRICHED TANAPROGET AND PROCESSES FOR ITS PREPARATION | TEVA WOMEN'S HEALTH, INC. (US) | 2014-09-18 | — | — | WO | disclosed |