SCHEMBL16059586

SCHEMBL16059586

CC1COCCC1N1CCNC1=O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3C3 Q8NEB9 10/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16178141 0.76 IL4I1 (0.35) PIK3C3
SCHEMBL16060642 0.76 IL4I1 (0.35) PIK3C3
SCHEMBL16061182 0.76 IL4I1 (0.35) PIK3C3
SCHEMBL11387954 0.73 HTR2A (0.36)
SCHEMBL16058949 0.72 CHRM2 (0.34)
SCHEMBL16058686 0.71 HSD11B1 (0.35)
SCHEMBL13931068 0.69
SCHEMBL17599191 0.65
SCHEMBL12385845 0.65 HSD11B1 (0.39)
SCHEMBL13450563 0.65 HSD11B1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014145015-A2 IMIDAZOLIDINONES AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITIES DECIPHERA PHARMACEUTICALS, LLC (US) 2014-09-18 WO disclosed