SCHEMBL16059672

SCHEMBL16059672

NC(=O)N1CCN(C2CCOCC2)C1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3590803 0.76 HRH3 (0.55) HRH3
SCHEMBL5779438 0.74 L3MBTL3 (0.55) HRH3
SCHEMBL23712050 0.74 SMN1; SMN2 (0.55) HRH3
Hydrochloric Acid SCHEMBL28848374 0.72 HRH3 (0.44) HRH3
SCHEMBL15415482 0.71 HRH3 (0.44) HRH3
SCHEMBL15415485 0.71 HRH3 (0.44) HRH3
SCHEMBL3216528 0.71 POLB (0.55) HRH3
SCHEMBL3861494 0.70 CHRM1 (0.51) HRH3
SCHEMBL23711619 0.70 HRH3 (0.50) HRH3
SCHEMBL3592203 0.70 HRH3 (0.58) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014145015-A2 IMIDAZOLIDINONES AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITIES DECIPHERA PHARMACEUTICALS, LLC (US) 2014-09-18 WO claimed