SCHEMBL5779438

SCHEMBL5779438

NC(=O)N1CCC(N2CCOCC2)CC1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
LMNA P02545 1/20 0.47
KDM4E B2RXH2 4/20 0.45
ALDH1A1 P00352 3/20 0.45
EPHX2 P34913 2/20 0.44
ACHE P22303 1/20 0.44
CBX7 O95931 1/20 0.42
CDYL2 Q8N8U2 1/20 0.42
CDYL Q9Y232 1/20 0.42
CDY1; CDY1B Q9Y6F8 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CHRM1 P11229 1/20 0.41
ACACB O00763 1/20 0.40
ACACA Q13085 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
MBTD1 Q05BQ5 1/20 0.40
TP53BP1 Q12888 1/20 0.40
L3MBTL4 Q8NA19 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31622193 0.89 L3MBTL3 (0.49) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL27991280 0.84 L3MBTL3 (0.58) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL24159209 0.82 L3MBTL3 (0.41) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL4315788 0.82 L3MBTL3 (0.57) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL6108511 0.82 L3MBTL3 (0.56) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL8143643 0.81 L3MBTL3 (0.55) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL8144136 0.81 SMN1; SMN2 (0.61) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL29033745 0.81 L3MBTL3 (0.47) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL1837999 0.81 L3MBTL3 (0.47) L3MBTL3L3MBTL1LMNAKDM4EALDH1A1
SCHEMBL5367596 0.80 L3MBTL3 (0.58) L3MBTL3L3MBTL1KDM4EALDH1A1MBTD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115916776-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2023-04-04 CN disclosed
WO-2007106705-A1 SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-09-20 WO disclosed
EP-1724271-A1 PREVENTIVE AND/OR THERAPEUTIC AGENT FOR NEUTROPHILIC INFLAMMATION DISEASE KYOWA HAKKO KOGYO CO., LTD. (JP) 2006-11-22 EP disclosed