SCHEMBL16059779

SCHEMBL16059779

CC(C)(C)OC(=O)C(CCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.58
▸ MDM4 O15151 2/20 0.51
▸ TP53 P04637 2/20 0.51
▸ TLR2 O60603 2/20 0.50
▸ CASP3 P42574 1/20 0.48
▸ IDO1 P14902 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28124458 0.98 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3
SCHEMBL29851790 0.98 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3
SCHEMBL16059782 0.92 MDM2 (0.55) MDM2MDM4TP53TLR2CASP3
SCHEMBL6740719 0.90 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL28928924 0.90 MDM2 (0.57) MDM2MDM4TP53TLR2CASP3
SCHEMBL34468451 0.89 MDM4 (0.54) MDM2MDM4TP53CASP3IDO1
SCHEMBL15630864 0.89 MDM4 (0.54) MDM2MDM4TP53CASP3IDO1
SCHEMBL15630865 0.89 MDM4 (0.54) MDM2MDM4TP53CASP3IDO1
SCHEMBL20211701 0.89 MDM4 (0.54) MDM2MDM4TP53CASP3IDO1
SCHEMBL25357881 0.88 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4169944-A1 PROCESS FOR PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2023-04-26 — — EP disclosed
EP-3701971-B1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-07-06 — — EP disclosed
EP-3611180-B1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2021-12-22 — — EP disclosed
EP-3701971-A1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2020-09-02 — — EP disclosed
EP-3611180-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2020-02-19 — — EP disclosed
EP-3116486-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2017-01-18 — — EP disclosed
EP-2968495-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2016-01-20 — — EP disclosed
WO-2015138907-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE CAPON DANIEL J (US) 2015-09-17 — — WO disclosed
WO-2014144911-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE CAPON DANIEL J (US) 2014-09-18 — — WO disclosed
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