SCHEMBL16059782

SCHEMBL16059782

CC(C)(C)OC(=O)C(CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.55
▸ MDM4 O15151 2/20 0.53
▸ TP53 P04637 2/20 0.53
▸ TLR2 O60603 2/20 0.49
▸ CASP3 P42574 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29851790 0.94 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3
SCHEMBL28124458 0.94 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3
SCHEMBL16059779 0.92 MDM2 (0.58) MDM2MDM4TP53TLR2CASP3
SCHEMBL15630864 0.90 MDM4 (0.54) MDM2MDM4TP53CASP3
SCHEMBL34468451 0.90 MDM4 (0.54) MDM2MDM4TP53CASP3
SCHEMBL15630865 0.90 MDM4 (0.54) MDM2MDM4TP53CASP3
SCHEMBL20211701 0.90 MDM4 (0.54) MDM2MDM4TP53CASP3
SCHEMBL27680742 0.90 MDM2 (0.54) MDM2MDM4TP53TLR2CASP3
SCHEMBL5969952 0.88 MDM4 (0.54) MDM2MDM4TP53CASP3
SCHEMBL29352017 0.87 MDM2 (0.55) MDM2MDM4TP53TLR2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2025-12-30 — — US disclosed
CN-118384290-A Hybrid immunoglobulins containing non-peptide linkages 生物分子控股有限责任公司 2024-07-26 — — CN disclosed
EP-4169944-A1 PROCESS FOR PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2023-04-26 — — EP disclosed
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-09-01 — — US disclosed
EP-4039281-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Biomolecular Holdings LLC (US) 2022-08-10 — — EP disclosed
EP-3701971-B1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2022-07-06 — — EP disclosed
US-11220556-B2 Hybrid immunoglobulin containing non-peptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2022-01-11 — — US disclosed
EP-3611180-B1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2021-12-22 — — EP disclosed
US-20210340222-A1 HYBRID IMMUNOGLOBULIN CONTAINING NONPEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC (US) 2021-11-04 — — US disclosed
US-11066459-B2 Hybrid immunoglobulin containing non-peptidyl linkage BIOMOLECULAR HOLDINGS LLC (US) 2021-07-20 — — US disclosed
EP-3701971-A1 COMPOUNDS USEFUL IN PREPARING HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2020-09-02 — — EP disclosed
EP-3611180-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2020-02-19 — — EP disclosed
EP-2968495-B1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE CAPON DANIEL J (US) 2019-07-03 — — EP disclosed
US-20170008950-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC 2017-01-12 — — US disclosed
EP-2968495-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE Capon, Daniel J. (US) 2016-01-20 — — EP disclosed
WO-2014144911-A2 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE CAPON DANIEL J (US) 2014-09-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066459-B2 Hybrid immunoglobulin containing non-peptidyl linkage FCGR3B, FCGR2A, SCLY MDM2 4485/4885MDM4 4458/4885TP53 3415/4885
US-20220275108-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, FCGR2A, VSIG8 MDM2 4693/4885MDM4 4598/4885TP53 2848/4885
US-11220556-B2 Hybrid immunoglobulin containing non-peptidyl linkage FCGR3B, FCGR2A, VSIG8 MDM2 4396/4885MDM4 3802/4885TP53 2258/4885
US-20210340222-A1 HYBRID IMMUNOGLOBULIN CONTAINING NONPEPTIDYL LINKAGE FCGR3B, FCGR2A, SCLY MDM2 4233/4885MDM4 4458/4885TP53 3309/4885
US-20170008950-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, SCLY, FCGR2A MDM2 4483/4885MDM4 4416/4885TP53 3160/4885
US-12509502-B2 Hybrid immunoglobulin containing nonpeptidyl linkage FCGR2A, FCGR3B, CD74 MDM2 3930/4885MDM4 4781/4885TP53 3409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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