Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26036814 | 0.91 | KMT2A (0.47) | ELANEALOX15KMT2AMEN1ADRB2 | |
| SCHEMBL19355097 | 0.91 | FABP7 (0.48) | ELANEALOX15KMT2AMEN1ADRB2 | |
| SCHEMBL15547599 | 0.89 | ALOX15 (0.55) | ELANEALOX15KMT2AMEN1ADRB2 | |
| SCHEMBL23518659 | 0.89 | FABP3 (0.49) | ELANEKMT2AMEN1ADRB2ALDH1A1 | |
| Bromide SCHEMBL16050020 | 0.87 | ALOX15 (0.53) | ELANEALOX15KMT2AMEN1ADRB2 | |
| SCHEMBL17430642 | 0.83 | ALOX15 (0.38) | ELANEALOX15KMT2AMEN1ADRB2 | |
| SCHEMBL10713156 | 0.82 | CA1 (0.48) | ELANEALOX15KMT2AMEN1ADRB2 | |
| SCHEMBL4090809 | 0.82 | KMT2A (0.55) | ELANEALOX15KMT2AALDH1A1MAPT | |
| SCHEMBL11239025 | 0.82 | ELANE (0.47) | ELANEALOX15KMT2AMEN1ADRB2 | |
| SCHEMBL1261877 | 0.82 | MEN1 (0.51) | ELANEALOX15KMT2AMEN1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10900941-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2021-01-26 | — | — | US | disclosed |
| US-10788471-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-10788471-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2020-09-29 | — | — | US | disclosed |
| US-20180364206-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY | 2018-12-20 | — | — | US | disclosed |
| US-20180292370-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | UNIV GEORGETOWN (US) | 2018-10-11 | — | — | US | disclosed |
| US-10012627-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2018-07-03 | — | — | US | disclosed |
| US-10012627-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2018-07-03 | — | — | US | disclosed |
| US-10012627-B2 | Determining stereoisomeric excess, concentration and absolute configuration | GEORGETOWN UNIVERSITY (US) | 2018-07-03 | — | — | US | disclosed |
| US-20160011156-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY | 2016-01-14 | — | — | US | disclosed |
| US-20160011156-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY | 2016-01-14 | — | — | US | disclosed |
| US-20160011156-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY | 2016-01-14 | — | — | US | disclosed |
| WO-2014145251-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014145251-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY (US) | 2014-09-18 | — | — | WO | disclosed |