Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16060611 | 0.83 | ELANE (0.49) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL4666170 | 0.76 | ALOX15 (0.47) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL12863857 | 0.75 | MTNR1A (0.55) | KMT2AMEN1 | |
| SCHEMBL26036814 | 0.75 | KMT2A (0.47) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL19355097 | 0.75 | FABP7 (0.48) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL27993666 | 0.75 | ALOX15 (0.44) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL11295860 | 0.75 | EPHX1 (0.48) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL27674000 | 0.75 | ALOX15 (0.46) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL15547599 | 0.74 | ALOX15 (0.55) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL23518659 | 0.73 | FABP3 (0.49) | ADRB2ELANEPTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160011156-A1 | DETERMINING STEREOISOMERIC EXCESS, CONCENTRATION AND ABSOLUTE CONFIGURATION | GEORGETOWN UNIVERSITY | 2016-01-14 | — | — | US | disclosed |