Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.40 |
| ▸ | HEXB | P07686 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3403614 | 0.81 | KDM4E (0.55) | ALDH1A1DHFRMAPTLMNAKDM4E | |
| Ammonia Solution, Strong SCHEMBL28485616 | 0.73 | KDM4E (0.45) | ALDH1A1MAPTLMNAMAPK1L3MBTL1 | |
| SCHEMBL23402852 | 0.70 | ALDH1A1 (0.44) | ALDH1A1DHFRMAPTLMNAMAPK1 | |
| SCHEMBL22567087 | 0.68 | KHK (0.47) | ALDH1A1DHFRMAPTLMNAPDE4A | |
| SCHEMBL23402531 | 0.68 | ALDH1A1 (0.45) | ALDH1A1DHFRMAPTLMNAMAPK1 | |
| SCHEMBL23398573 | 0.68 | ALDH1A1 (0.45) | ALDH1A1DHFRMAPTLMNAMAPK1 | |
| SCHEMBL23401898 | 0.68 | ALDH1A1 (0.42) | ALDH1A1DHFRMAPTLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL22559675 | 0.68 | KHK (0.46) | ALDH1A1DHFRMAPTLMNAPDE4A | |
| Hydrochloric Acid SCHEMBL29369186 | 0.68 | KHK (0.46) | ALDH1A1DHFRMAPTLMNAPDE4A | |
| SCHEMBL23402183 | 0.67 | ALDH1A1 (0.44) | ALDH1A1DHFRMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288066-A1 | METHODS AND COMPOSITIONS FOR REGENERATING HAIR CELLS IN THE INNER EAR OF ADULT MAMMALS | Massachusetts Eye and Ear Infirmary (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2014145205-A2 | METHODS AND COMPOSITIONS OF P27KIP1 TRANSCRIPTION MODULATORS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2014-09-18 | — | — | WO | disclosed |