Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16060957 | 0.95 | ALDH1A1 (0.33) | ALDH1A1KMT2ASCN9A | |
| SCHEMBL16059449 | 0.85 | ALDH1A1 (0.34) | ALDH1A1KMT2A | |
| SCHEMBL20394931 | 0.83 | SCN9A (0.33) | SCN9A | |
| SCHEMBL16880936 | 0.81 | AKT1 (0.35) | — | |
| SCHEMBL16059401 | 0.80 | SCN9A (0.44) | KMT2ASCN9A | |
| SCHEMBL16060152 | 0.80 | SCN9A (0.57) | SCN9A | |
| SCHEMBL16059924 | 0.79 | KMT2A (0.36) | ALDH1A1KMT2A | |
| SCHEMBL16061036 | 0.79 | SCN9A (0.33) | SCN9A | |
| SCHEMBL16061818 | 0.79 | SCN9A (0.44) | ALDH1A1KMT2ASCN9A | |
| SCHEMBL16061984 | 0.77 | SCN9A (0.32) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970156-A2 | SUBSTITUTED BENZOXAZOLES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144545-A2 | SUBSTITUTED BENZOXAZOLES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2014-09-18 | — | — | WO | disclosed |