Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16059924 | 0.94 | KMT2A (0.36) | ALDH1A1KMT2ANPC1POLBRAB9A | |
| SCHEMBL16062000 | 0.85 | ALDH1A1 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL16880943 | 0.82 | MAPT (0.46) | KMT2APOLBFAAH | |
| SCHEMBL16060957 | 0.79 | ALDH1A1 (0.33) | ALDH1A1KMT2AFAAH | |
| SCHEMBL16059401 | 0.77 | SCN9A (0.44) | KMT2APOLB | |
| SCHEMBL17981237 | 0.76 | PDPK1 (0.32) | — | |
| SCHEMBL16880936 | 0.76 | AKT1 (0.35) | FAAH | |
| SCHEMBL16061036 | 0.76 | SCN9A (0.33) | — | |
| SCHEMBL20394931 | 0.76 | SCN9A (0.33) | — | |
| SCHEMBL1759441 | 0.75 | MAPT (0.46) | POLBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970156-A2 | SUBSTITUTED BENZOXAZOLES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144545-A2 | SUBSTITUTED BENZOXAZOLES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2014-09-18 | — | — | WO | disclosed |