Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16062676 | 0.95 | HRH2 (0.37) | HRH2HRH1DGKAMEN1KMT2A | |
| SCHEMBL22743444 | 0.91 | HRH2 (0.42) | HRH2HRH1MEN1KMT2AEPHX2 | |
| SCHEMBL16062668 | 0.90 | ALDH1A1 (0.35) | HRH2HRH1DGKAMEN1KMT2A | |
| SCHEMBL14651718 | 0.89 | HRH2 (0.38) | HRH2HRH1DGKAMEN1KMT2A | |
| SCHEMBL16062673 | 0.88 | HRH2 (0.36) | HRH2HRH1DGKAMEN1KMT2A | |
| SCHEMBL16062671 | 0.86 | HRH2 (0.45) | HRH2HRH1DGKAMEN1KMT2A | |
| SCHEMBL14012683 | 0.85 | MEN1 (0.38) | HRH2HRH1MEN1KMT2AALDH1A1 | |
| SCHEMBL14012692 | 0.85 | MEN1 (0.38) | HRH2HRH1MEN1KMT2AALDH1A1 | |
| SCHEMBL14012680 | 0.85 | MEN1 (0.38) | HRH2HRH1MEN1KMT2AALDH1A1 | |
| SCHEMBL5421607 | 0.83 | THRB (0.42) | DGKAALDH1A1MAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835492-B2 | Temperature and pH sensitive block copolymer and polymeric hydrogels using the same | SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2014-09-16 | — | — | US | disclosed |