Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | DNA2 | P51530 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | DTYMK | P23919 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10024457 | 0.90 | TSHR (0.48) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL10024482 | 0.87 | TSHR (0.50) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL10024450 | 0.84 | TSHR (0.46) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL16573837 | 0.80 | KDM4E (0.41) | TSHRALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL21802325 | 0.76 | TSHR (0.58) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2213952 | 0.76 | TSHR (0.62) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL2762222 | 0.72 | TSHR (0.54) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9657224 | 0.71 | TSHR (0.53) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9087640 | 0.70 | TSHR (0.51) | TSHRALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL16063177 | 0.69 | MAPT (0.41) | TSHRALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732382-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150079603-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-03-19 | — | — | US | disclosed |
| US-8834847-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8834847-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-09-16 | — | — | US | disclosed |