SCHEMBL16062800

SCHEMBL16062800

COC(=O)CCCO[C@@H]1OC(CO[C@H]2OC(CO)[C@@H](C)[C@H](C)C2OC(=O)c2ccccc2)[C@@H](C)[C@H](O)C1OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 1/20 0.41
▸ SELP P16109 6/20 0.40
▸ LGALS3 P17931 3/20 0.38
▸ LGALS9 O00182 1/20 0.38
▸ LGALS1 P09382 1/20 0.38
▸ LGALS7; LGALS7B P47929 1/20 0.38
▸ MAOB P27338 1/20 0.38
▸ NT5E P21589 1/20 0.37
▸ MCHR1 Q99705 2/20 0.37
▸ SSTR2 P30874 2/20 0.37
▸ SSTR3 P32745 2/20 0.37
▸ SSTR5 P35346 2/20 0.37
▸ LGALS4 P56470 1/20 0.37
▸ TACR1 P25103 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16062799 0.89 NT5E (0.39) SELPNT5EMCHR1SSTR2SSTR3
SCHEMBL16062805 0.88 NT5E (0.36) LGALS8SELPLGALS3NT5ESSTR2
SCHEMBL21537963 0.87 SELP (0.43) LGALS8SELPLGALS3LGALS9LGALS1
SCHEMBL16849996 0.87 LMNA (0.40) LGALS8SELPNT5EMCHR1SSTR2
SCHEMBL16062803 0.85 NT5E (0.36) LGALS8SELPLGALS3NT5EMCHR1
SCHEMBL16062798 0.85 LGALS8 (0.45) LGALS8SELPMCHR1SSTR2SSTR3
SCHEMBL16062804 0.85 NT5E (0.38) SELPNT5EMCHR1SSTR2SSTR3
SCHEMBL16062808 0.84 CD209 (0.42) LGALS8SELPLGALS3LGALS9LGALS1
SCHEMBL16062802 0.83 SELP (0.38) SELPNT5EMCHR1SSTR2SSTR3
SCHEMBL26443696 0.82 MEN1 (0.41) SELPLGALS3LGALS9LGALS1LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180002365-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2018-01-04 — — US disclosed
US-9493498-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2016-11-15 — — US disclosed
US-20150175643-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2015-06-25 — — US disclosed
US-8835614-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2014-09-16 — — US disclosed
US-20110300120-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2011-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110300120-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 LGALS8 404/4885SELP 1706/4885LGALS3 615/4885
US-20150175643-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 LGALS8 404/4885SELP 1706/4885LGALS3 615/4885
US-20180002365-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 LGALS8 404/4885SELP 1706/4885LGALS3 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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