Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15678121 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL14853737 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL16063071 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL15678111 | 0.84 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL16063059 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL22266761 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL24674068 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL22797615 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL22799362 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPK1GAAPOLB | |
| SCHEMBL24673603 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPK1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835615-B2 | 2′-fluorine-4′-substituted-nucleoside analogues, preparation methods and uses thereof | HENAN GENUINE BIOTECH CO., LTD. (CN) | 2014-09-16 | — | — | US | disclosed |