Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853737 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAPOLBMAPK1 | |
| SCHEMBL16063062 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HPGDGAAPOLBMAPK1 | |
| SCHEMBL16063070 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAPOLBMAPK1 | |
| SCHEMBL9919246 | 0.81 | GAA (0.40) | ALDH1A1GAAABCB1LMNANPC1 | |
| SCHEMBL14853745 | 0.79 | GAA (0.43) | ALDH1A1GAAABCB1LMNANPC1 | |
| SCHEMBL15678121 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HPGDGAAPOLBMAPK1 | |
| SCHEMBL22335650 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HPGDGAAPOLBMAPK1 | |
| SCHEMBL14853753 | 0.78 | ABCB1 (0.45) | ALDH1A1GAAMAPK1ABCB1MAPT | |
| SCHEMBL9919245 | 0.78 | ABCB1 (0.40) | ALDH1A1GAAABCB1LMNA | |
| SCHEMBL16063058 | 0.78 | ABCB1 (0.40) | ALDH1A1GAAABCB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835615-B2 | 2′-fluorine-4′-substituted-nucleoside analogues, preparation methods and uses thereof | HENAN GENUINE BIOTECH CO., LTD. (CN) | 2014-09-16 | — | — | US | disclosed |