Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16063072 | 0.90 | ABCB1 (0.40) | ABCB1 | |
| SCHEMBL16063064 | 0.88 | ABCB1 (0.37) | MAPK1HIF1AABCB1MAPTLMNA | |
| SCHEMBL16063058 | 0.83 | ABCB1 (0.40) | ABCB1LMNAALDH1A1 | |
| SCHEMBL9919245 | 0.83 | ABCB1 (0.40) | ABCB1LMNAALDH1A1 | |
| SCHEMBL17359828 | 0.82 | ABCB1 (0.40) | ABCB1 | |
| SCHEMBL16063070 | 0.76 | ALDH1A1 (0.51) | MAPK1HIF1AABCB1MAPTLMNA | |
| SCHEMBL9917067 | 0.76 | GAA (0.41) | ABCB1TSHR | |
| SCHEMBL25398613 | 0.75 | MAPT (0.41) | MAPK1HIF1AABCB1MAPTLMNA | |
| SCHEMBL6099509 | 0.74 | MAPT (0.42) | MAPK1HIF1AABCB1MAPTLMNA | |
| SCHEMBL6099512 | 0.74 | MAPT (0.42) | MAPK1HIF1AABCB1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835615-B2 | 2′-fluorine-4′-substituted-nucleoside analogues, preparation methods and uses thereof | HENAN GENUINE BIOTECH CO., LTD. (CN) | 2014-09-16 | — | — | US | disclosed |