Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 13/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9919245 | 0.88 | ABCB1 (0.40) | GAAABCB1 | |
| SCHEMBL16063058 | 0.88 | ABCB1 (0.40) | GAAABCB1 | |
| SCHEMBL9917066 | 0.85 | GAA (0.43) | GAAABCB1TSHRCHRNA7MEN1 | |
| SCHEMBL9917065 | 0.84 | GAA (0.42) | GAAABCB1TSHRCHRNA7MEN1 | |
| SCHEMBL26268684 | 0.81 | ABCB1 (0.47) | GAAABCB1 | |
| SCHEMBL16063060 | 0.78 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL16063065 | 0.76 | MAPK1 (0.35) | ABCB1TSHR | |
| SCHEMBL6099624 | 0.75 | ABCB1 (0.43) | GAAABCB1 | |
| SCHEMBL16063068 | 0.75 | ABCB1 (0.41) | GAAABCB1 | |
| SCHEMBL6099628 | 0.75 | ABCB1 (0.43) | GAAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149657-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (AL) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149657-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SLC29A2, DUT, SLC29A1 | GAA 614/4885ABCB1 163/4885TSHR 3802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.