Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | DRD4 | P21917 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23067879 | 0.85 | DRD2 (0.84) | DRD2DRD4DRD3F2POLB | |
| SCHEMBL31663663 | 0.85 | DRD2 (0.84) | DRD2DRD4DRD3F2POLB | |
| SCHEMBL15829982 | 0.84 | DRD2 (0.66) | DRD2DRD4DRD3F2POLB | |
| SCHEMBL27465 | 0.82 | DRD2 (0.62) | DRD2DRD4DRD3F2POLB | |
| SCHEMBL29381067 | 0.82 | DRD2 (0.62) | DRD2DRD4DRD3F2POLB | |
| SCHEMBL14308606 | 0.82 | DRD2 (0.69) | DRD2DRD4DRD3F2POLB | |
| SCHEMBL11455127 | 0.82 | DRD2 (0.64) | DRD2DRD4DRD3F2POLB | |
| SCHEMBL11674802 | 0.81 | DRD2 (0.66) | DRD2DRD4DRD3F2KMT2A | |
| SCHEMBL7323942 | 0.79 | DRD2 (0.60) | DRD2DRD4DRD3F2KMT2A | |
| SCHEMBL4733971 | 0.79 | DRD2 (0.56) | DRD2DRD4DRD3F2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376430-B2 | Broad spectrum benzothiophene-nitrothiazolide and other antimicrobials | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-06-28 | — | — | US | disclosed |
| US-9333193-B2 | Compositions and methods for treating tuberculosis | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-05-10 | — | — | US | disclosed |
| US-8835644-B2 | Broad spectrum benzothiophene-nitrothiazolide and other antimicrobials | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2014-09-16 | — | — | US | disclosed |