Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323942 | 0.92 | DRD2 (0.60) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL6304467 | 0.90 | DRD2 (0.58) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL20530524 | 0.89 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL20530515 | 0.89 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL27465 | 0.87 | DRD2 (0.62) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL29381067 | 0.87 | DRD2 (0.62) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL11674802 | 0.85 | DRD2 (0.66) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL11613393 | 0.83 | ACHE (0.56) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL10798638 | 0.83 | DRD2 (0.64) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL2063136 | 0.82 | DRD2 (0.72) | DRD2DRD4DRD3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368194-B | Method for producing (meth) acryloyl group-terminated polyisobutylene polymer | 株式会社钟化 | 2021-03-19 | — | — | CN | disclosed |
| US-10604598-B2 | Method of producing (meth)acryloyl-terminated polyisobutylene polymer | KANEKA CORPORATION (JP) | 2020-03-31 | — | — | US | disclosed |
| US-20180362676-A1 | METHOD OF PRODUCING (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER | KANEKA CORPORATION (JP) | 2018-12-20 | — | — | US | disclosed |
| EP-3388454-A1 | METHOD OF PRODUCING (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER | Kaneka Corporation (JP) | 2018-10-17 | — | — | EP | disclosed |
| EP-3052496-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| WO-2015049574-A1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-09 | — | — | WO | disclosed |
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1243582-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0984963-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054180-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-12-03 | — | — | WO | disclosed |
| US-5081099-A | A tetrahydronaphthalene sensitizer as antifogging agent; storage stability | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | DRD2 621/4885DRD4 962/4885DRD3 970/4885 |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | DRD2 747/4885DRD4 932/4885DRD3 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.