Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226526 | 0.84 | CES2 (0.61) | MAPTMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL30628238 | 0.84 | MAPT (0.51) | MAPTMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL1521930 | 0.84 | MAPT (0.51) | MAPTMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL30628241 | 0.84 | MAPT (0.51) | MAPTMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL2706971 | 0.84 | TDP1 (0.51) | MAPTMEN1KMT2AHPGDKDM4E | |
| SCHEMBL2546863 | 0.84 | TSHR (0.55) | KMT2AHPGDTDP1TSHRTLR4 | |
| SCHEMBL3413087 | 0.84 | MAPT (0.47) | MAPTMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL3413089 | 0.84 | MAPT (0.47) | MAPTMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL15094236 | 0.84 | MAPT (0.46) | MAPTMEN1LMNACYP1A2CYP2C9 | |
| SCHEMBL28474047 | 0.83 | CA12 (0.53) | MAPTMEN1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014142308-A1 | BICYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | 公益財団法人相模中央化学研究所 (JP) | 2014-09-18 | — | — | WO | disclosed |