Sugi Predict

Sugi Predict / Compounds / SCHEMBL2546863

SCHEMBL2546863

SCHEMBL2546863

CCOC(=O)c1ccc(F)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.55
▸ CYP4F2 P78329 1/20 0.51
▸ CYP4A11 Q02928 1/20 0.51
▸ BAZ2B Q9UIF8 1/20 0.51
▸ BAZ2A Q9UIF9 1/20 0.51
▸ CA12 O43570 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ CA2 P00918 1/20 0.50
▸ CA7 P43166 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ CA14 Q9ULX7 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ TLR4 O00206 3/20 0.49
▸ NR3C2 P08235 1/20 0.48
▸ HPGD P15428 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ MAPK1 P28482 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20267301 0.87 ALDH1A1 (0.53) TSHRTDP1L3MBTL1HPGDALOX15
SCHEMBL11801981 0.87 CYP4F2 (0.63) TSHRCYP4F2CYP4A11BAZ2BBAZ2A
SCHEMBL13296383 0.84 TSHR (0.55) TSHRTDP1L3MBTL1HPGDALOX15
SCHEMBL4628672 0.84 TSHR (0.60) TSHRCA12CA1CA2CA7
SCHEMBL1958231 0.84 TSHR (0.47) TSHRCYP4F2CYP4A11CA12CA1
SCHEMBL16063530 0.84 MAPT (0.49) TSHRTDP1TLR4HPGDRAB9A
SCHEMBL522136 0.83 KMT2A (0.59) TSHRCYP4F2CYP4A11BAZ2BBAZ2A
SCHEMBL367075 0.83 TSHR (0.57) TSHRCA12CA1CA2CA7
SCHEMBL9827284 0.83 BAZ2B (0.58) TSHRCYP4F2CYP4A11BAZ2BBAZ2A
SCHEMBL5247862 0.83 TSHR (0.57) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085051-A1 PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID ADAMA AGAN LTD. (IL) 2026-03-26 — — US disclosed
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 — — US disclosed
CN-119790033-A Preparation of 2-chloro-4-fluoro-5-nitrobenzoic acid 安道麦阿甘有限公司 2025-04-08 — — CN disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 — — US disclosed
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors ENANTA PHARM INC (US) 2024-10-31 — — US disclosed
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2024-04-09 — — US disclosed
EP-3687543-B1 COMBINATIONS OF PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-03-20 — — EP disclosed
EP-4289824-A1 URACIL COMPOUND CONTAINING CARBOXYLATE FRAGMENT AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE Jiangsu Flag Chemical Industry Co., Ltd. (CN) 2023-12-13 — — EP disclosed
CN-111386118-B Combination pharmaceutical agents as RSV inhibitors 英安塔制药有限公司 2023-05-09 — — CN disclosed
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2023-03-23 — — US disclosed
WO-2009111676-A2 BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS ANACOR PHARMACEUTICALS, INC (US) 2009-09-11 — — WO disclosed
EP-1863483-A1 BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS Janssen Pharmaceutica, N.V. (BE) 2007-12-12 — — EP disclosed
US-20060223810-A1 Bicyclic pyrazole compounds as antibacterial agents JANSSEN PHARMACEUTICA N.V. (BE) 2006-10-05 — — US disclosed
WO-2006105289-A1 BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS JANSSEN PHARMACEUTICA N.V. (BE) 2006-10-05 — — WO disclosed
EP-1227083-A1 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS MEIJI SEIKA KAISHA LTD. (JP) 2002-07-31 — — EP disclosed
WO-1999020606-A2 PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS J. URIACH & CIA. S.A. (ES) 1999-04-29 — — WO disclosed
US-5753682-A Imidazole lipoxygenase inhibitors PFIZER INC. (US) 1998-05-19 — — US disclosed
EP-0703913-B1 IMIDAZOLES AS LIPOXYGENASE INHIBITORS PFIZER (US) 1997-06-11 — — EP disclosed
EP-0703913-A1 IMIDAZOLE LIPOXYGENASE INHIBITORS PFIZER (US) 1996-04-03 — — EP disclosed
WO-1994029299-A1 IMIDAZOLE LIPOXYGENASE INHIBITORS PFIZER INC. (US) 1994-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors GABRA5, GABRA1, GABBR2 TSHR 1396/4885CYP4F2 134/4885CYP4A11 45/4885
US-20060223810-A1 Bicyclic pyrazole compounds as antibacterial agents NOD2, BAK1, CASP3 TSHR 4510/4885CYP4F2 2817/4885CYP4A11 2768/4885
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 TSHR 1396/4885CYP4F2 134/4885CYP4A11 45/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 TSHR 1396/4885CYP4F2 134/4885CYP4A11 45/4885
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 TSHR 1396/4885CYP4F2 134/4885CYP4A11 45/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 TSHR 4229/4885CYP4F2 4002/4885CYP4A11 2436/4885
US-20260085051-A1 PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID FOSB, DDT, NPM1 TSHR 2588/4885CYP4F2 235/4885CYP4A11 1277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.