Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | CPA2 | P48052 | 1/20 | 0.46 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CHRND | Q07001 | 5/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5009890 | 0.87 | GRIA1 (0.62) | GRIA1CTSSCTSKCPA1MME | |
| SCHEMBL5007773 | 0.87 | GRIA1 (0.62) | GRIA1CTSSCTSKCPA1MME | |
| SCHEMBL16116805 | 0.86 | ACACB (0.51) | — | |
| SCHEMBL18647567 | 0.85 | ACACB (0.55) | — | |
| SCHEMBL16116808 | 0.85 | GRIA1 (0.56) | GRIA1CTSSCTSKCPA1MME | |
| SCHEMBL30493613 | 0.84 | GRIA1 (0.55) | GRIA1CTSSCTSKCPA1MME | |
| SCHEMBL25139820 | 0.83 | GRIA1 (0.57) | GRIA1CTSSCTSKCPA1MME | |
| SCHEMBL24724924 | 0.83 | GRIA1 (0.57) | GRIA1CTSSCTSKCPA1MME | |
| SCHEMBL12632559 | 0.83 | GRIA1 (0.57) | GRIA1CTSSCTSKCPA1MME | |
| SCHEMBL6862498 | 0.83 | GRIA1 (0.57) | GRIA1CTSSCTSKCPA1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015077303-A1 | PATIENT SELECTION METHOD FOR INFLAMMATION | PURDUE RESEARCH FOUNDATION (US) | 2015-05-28 | — | — | WO | disclosed |
| WO-2014149073-A1 | METHODS OF MANUFACTURE AND SYNTHESIS OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR TARGETED IMAGING OF TUMORS | ON TARGET LABORATORIES LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014149069-A1 | SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS | PURDUE RESEARCH FOUNDATION (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014143309-A1 | FLUORESCENCE IMAGING OF INFLAMMATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2014-09-18 | — | — | WO | disclosed |