Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | CPA2 | P48052 | 1/20 | 0.48 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493638 | 0.97 | GRIA1 (0.55) | GRIA1MMP9MMP8CTSSCTSK | |
| SCHEMBL25139820 | 0.87 | GRIA1 (0.57) | GRIA1MMP9MMP8CTSSCTSK | |
| SCHEMBL28747211 | 0.87 | ACACB (0.55) | GRIA1MMP8CTSSCTSKHDAC3 | |
| SCHEMBL24724924 | 0.87 | GRIA1 (0.57) | GRIA1MMP9MMP8CTSSCTSK | |
| SCHEMBL12632559 | 0.87 | GRIA1 (0.57) | GRIA1MMP9MMP8CTSSCTSK | |
| SCHEMBL8671866 | 0.86 | GRIA1 (0.60) | GRIA1CTSSCTSKFOLH1CPA1 | |
| SCHEMBL11522409 | 0.86 | GRIA1 (0.60) | GRIA1CTSSCTSKFOLH1CPA1 | |
| SCHEMBL8581074 | 0.86 | GRIA1 (0.60) | GRIA1CTSSCTSKFOLH1CPA1 | |
| SCHEMBL12641900 | 0.86 | GRIA1 (0.56) | GRIA1MMP9MMP8CTSSCTSK | |
| SCHEMBL16116808 | 0.86 | GRIA1 (0.56) | GRIA1MMP9MMP8CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054776-A9 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-03-03 | — | — | WO | disclosed |
| WO-2007054776-A2 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | disclosed |