Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19369220 | 0.96 | KMT2A (0.36) | KMT2ABLMALOX15PMP22DPP4 | |
| SCHEMBL12241922 | 0.82 | ALOX15 (0.38) | KMT2ABLMALOX15PMP22DPP4 | |
| SCHEMBL3184920 | 0.81 | TSHR (0.47) | KMT2ABLMPMP22MEN1CYP2C19 | |
| SCHEMBL5085648 | 0.81 | ALDH1A1 (0.38) | FAAHGRIK1GRIK2TSHR | |
| SCHEMBL3185229 | 0.81 | TSHR (0.47) | KMT2ABLMPMP22MEN1CYP2C19 | |
| SCHEMBL7865081 | 0.81 | GRIK1 (0.31) | FAAHGRIK1GRIK2TSHR | |
| SCHEMBL3184927 | 0.81 | TSHR (0.47) | KMT2ABLMPMP22MEN1CYP2C19 | |
| SCHEMBL7530291 | 0.79 | BLM (0.50) | KMT2ABLMALOX15PMP22DPP4 | |
| SCHEMBL9915018 | 0.79 | GRIK1 (0.39) | KMT2ABLMALOX15PMP22DPP4 | |
| SCHEMBL19866058 | 0.76 | KMT2A (0.36) | KMT2ABLMALOX15PMP22DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014145686-A2 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | SU ZHUANG (US) | 2014-09-18 | — | — | WO | disclosed |