Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768435 | 0.86 | NPSR1 (0.57) | HTTCYP1A2CYP2D6CYP2C19LMNA | |
| SCHEMBL10642253 | 0.80 | HTT (0.44) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1557309 | 0.79 | ALDH1A1 (0.47) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16055833 | 0.79 | ALDH1A1 (0.46) | LMNAALDH1A1NPSR1GPBAR1 | |
| SCHEMBL21531658 | 0.78 | NPSR1 (0.44) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15213234 | 0.75 | SLC9A1 (0.50) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14622854 | 0.75 | SLC9A1 (0.50) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15056188 | 0.75 | SLC9A1 (0.50) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1570974 | 0.75 | SLC9A1 (0.50) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13473785 | 0.74 | PDE4A (0.67) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-04-19 | — | — | US | disclosed |
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-04-19 | — | — | US | disclosed |
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | UNIV NANYANG TECH (SG) | 2019-11-07 | — | — | US | disclosed |
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-11 | — | — | US | disclosed |
| WO-2014142755-A1 | ACTIVATION OF CARBONYL β-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | HTT 4695/4885CYP1A2 29/4885CYP2D6 153/4885 |
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | HTT 4695/4885CYP1A2 29/4885CYP2D6 153/4885 |
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | CBR1, CBR3, CAT | HTT 4695/4885CYP1A2 29/4885CYP2D6 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.