Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.37 |
| ▸ | MAOA | P21397 | 8/20 | 0.37 |
| ▸ | MAOB | P27338 | 8/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16056849 | 1.00 | KDM1A (0.37) | KDM1AMAOAMAOBNFKB1NFKB2 | |
| SCHEMBL17525850 | 1.00 | KDM1A (0.37) | KDM1AMAOAMAOBNFKB1NFKB2 | |
| SCHEMBL16066029 | 0.92 | RORC (0.36) | KDM1AMAOBGAAKMT2A | |
| SCHEMBL16056190 | 0.92 | RORC (0.36) | KDM1AMAOBGAAKMT2A | |
| SCHEMBL17525817 | 0.92 | RORC (0.36) | KDM1AMAOBGAAKMT2A | |
| SCHEMBL16055519 | 0.90 | KDM1A (0.43) | KDM1AALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL16056074 | 0.90 | SLC6A9 (0.35) | MAOBSMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL16065918 | 0.90 | KDM1A (0.43) | KDM1AALDH1A1GAAMAPTCYP2C9 | |
| SCHEMBL17525849 | 0.90 | SLC6A9 (0.35) | MAOBSMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL16065916 | 0.90 | KDM1A (0.43) | KDM1AALDH1A1GAAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-04-19 | — | — | US | disclosed |
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | UNIV NANYANG TECH (SG) | 2019-11-07 | — | — | US | disclosed |
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-11 | — | — | US | disclosed |
| WO-2014142755-A1 | ACTIVATION OF CARBONYL β-CARBONS FOR CHEMICAL TRANSFORMATIONS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039827-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | KDM1A 3183/4885MAOA 239/4885MAOB 232/4885 |
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | KDM1A 3183/4885MAOA 239/4885MAOB 232/4885 |
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | CBR1, CBR3, CAT | KDM1A 3183/4885MAOA 239/4885MAOB 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.