SCHEMBL16066239

SCHEMBL16066239

c1ccc2c(c1)nc1c3ccccc3c3c4[nH]c5ccccc5c4ccc3n21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
CYP1A1 P04798 1/20 0.45
KEAP1 Q14145 1/20 0.45
CYP1B1 Q16678 1/20 0.45
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44
GABRA1 P14867 2/20 0.44
GABRB1 P18505 2/20 0.44
GABRG2 P18507 2/20 0.44
GABRB3 P28472 2/20 0.44
GABRA5 P31644 2/20 0.44
GABRA3 P34903 2/20 0.44
GABRA2 P47869 2/20 0.44
GABRB2 P47870 2/20 0.44
GABRA4 P48169 2/20 0.44
GABRE P78334 2/20 0.44
GABRA6 Q16445 2/20 0.44
GABRG1 Q8N1C3 2/20 0.44
GABRG3 Q99928 2/20 0.44
GABRQ Q9UN88 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16067066 0.88 CYP1A2 (0.46) CYP1A2CYP1A1KEAP1CYP1B1GABRP
SCHEMBL16067057 0.88 CYP1A2 (0.46) CYP1A2CYP1A1KEAP1CYP1B1GABRP
SCHEMBL16066433 0.84 CYP1A2 (0.47) CYP1A2CYP1A1KEAP1CYP1B1GABRP
SCHEMBL16066271 0.83 KDM4E (0.44) CYP1A2GABRPGABRDGABRA1GABRB1
SCHEMBL16066572 0.82 AHR (0.41) CYP1A2CYP1A1KEAP1CYP1B1GABRP
SCHEMBL21364405 0.82 KDM4E (0.49) CYP1A2CYP1A1KEAP1CYP1B1KDM4E
SCHEMBL21364400 0.79 KDM4E (0.45) CYP1A2CYP1A1KEAP1CYP1B1GABRP
SCHEMBL17033418 0.78 KIF11 (0.44) CYP1A2CYP1A1KEAP1CYP1B1GABRP
SCHEMBL23948639 0.77 CYP1A2 (0.40) CYP1A2CYP1A1KEAP1CYP1B1GABRP
SCHEMBL17996899 0.77 KDM4E (0.43) CYP1A2CYP1A1KEAP1CYP1B1GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014142488-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT INCLUDING SAME 주식회사 두산 (KR) 2014-09-18 WO disclosed