Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | PARN | O95453 | 1/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17456297 | 0.72 | CYP11B2 (0.53) | CYP11B2TNFCYP11B1TSHRALDH1A1 | |
| SCHEMBL22751731 | 0.70 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL17456294 | 0.70 | CYP11B2 (0.67) | CYP11B2TNFCYP11B1TSHRALDH1A1 | |
| SCHEMBL21499645 | 0.68 | GDA (0.46) | CYP11B2TNFCYP11B1TSHRALDH1A1 | |
| SCHEMBL28948229 | 0.68 | HTR2C (0.46) | CYP11B2TNFCYP11B1 | |
| SCHEMBL5880466 | 0.68 | HTR7 (0.44) | — | |
| SCHEMBL30595217 | 0.67 | PARN (0.54) | CYP11B2TNFCYP11B1TSHRKDM4C | |
| SCHEMBL5744489 | 0.67 | GDA (0.51) | CYP11B2TNFCYP11B1TSHRKDM4C | |
| Hydrochloric Acid SCHEMBL5880535 | 0.67 | HTR7 (0.43) | — | |
| SCHEMBL17456272 | 0.66 | CYP11B2 (0.61) | CYP11B2TNFCYP11B1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014143799-A2 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2014-09-18 | — | — | WO | disclosed |