Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865627 | 0.78 | CYP1A2 (0.46) | NAAAASAH1SIGMAR1 | |
| SCHEMBL16056471 | 0.78 | NAAA (0.40) | NAAAASAH1SIGMAR1 | |
| SCHEMBL8281750 | 0.78 | — | — | |
| SCHEMBL21710303 | 0.77 | CYP1A2 (0.45) | NAAAASAH1SIGMAR1 | |
| SCHEMBL12575131 | 0.77 | NAAA (0.37) | NAAAASAH1 | |
| SCHEMBL9225371 | 0.76 | — | — | |
| SCHEMBL18091610 | 0.76 | NAAA (0.38) | NAAAASAH1 | |
| SCHEMBL19304169 | 0.76 | CYP1A2 (0.54) | NAAAASAH1 | |
| SCHEMBL21065 | 0.75 | NAAA (0.34) | NAAAASAH1 | |
| SCHEMBL8281752 | 0.74 | SIGMAR1 (0.52) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144836-A2 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-18 | — | — | WO | disclosed |