SCHEMBL1606930

SCHEMBL1606930

C=CCc1cccc(Nc2cccc(CC=C)c2CC=C)c1CC=C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 3/20 0.37
MAPK1 P28482 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AKR1B1 P15121 1/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 2/20 0.34
POLB P06746 2/20 0.34
MTNR1A P48039 1/20 0.33
AURKA O14965 1/20 0.33
DAPK3 O43293 1/20 0.33
MAP4K4 O95819 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530697 0.88 MEN1 (0.48) GABRA1GABRB2ADRA2BADRA2CMEN1
SCHEMBL11494813 0.83 GABRA1 (0.42) GABRA1GABRB2ADRA2BADRA2CMEN1
SCHEMBL18136 0.83 GABRA1 (0.56) GABRA1GABRB2ADRA2BADRA2CMEN1
SCHEMBL10761705 0.81 CYP1A2 (0.50) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL176287 0.81 ADRA2C (0.47) GABRA1GABRB2ADRA2BADRA2CMEN1
SCHEMBL10387389 0.78 GABRA1 (0.63) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL31619949 0.78 GABRA1 (0.56) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL5831594 0.78 GABRA1 (0.56) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL616173 0.78 GABRA1 (0.52) GABRA1GABRB2MEN1KMT2AMAPT
SCHEMBL2362269 0.77 GABRA1 (0.61) GABRA1GABRB2ADRA2BADRA2CMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109642175-B Marine diesel engine cylinder lubricating oil composition 雪佛龙奥伦耐技术有限责任公司 2023-07-18 CN claimed
EP-3504307-B1 MARINE DIESEL CYLINDER LUBRICANT OIL COMPOSITIONS CHEVRON ORONITE TECH BV (NL) 2022-05-11 EP claimed
US-20240018440-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC 2024-01-18 US disclosed
EP-4263481-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER Huntsman Petrochemical LLC (US) 2023-10-25 EP disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
EP-2880140-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINES SHELL INT RESEARCH (NL) 2023-03-08 EP disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
WO-2022132364-A1 REACTION PRODUCT OF AN ORGANIC AMINE AND GLYCIDOL AND ITS USE AS A FRICTION MODIFIER HUNTSMAN PETROCHEMICAL LLC (US) 2022-06-23 WO disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
EP-3265546-B1 NOVEL ORGANIC FRICTION MODIFIERS HUNTSMAN PETROCHEMICAL LLC (US) 2021-12-29 EP disclosed
US-20050096236-A1 Ashless additive formulations suitable for hydraulic oil applications CHEVRON ORONITE S.A. 2005-05-05 US disclosed
US-20040224860-A1 Lubricating oil compositions SHELL OIL COMPANY 2004-11-11 US disclosed
US-20040214733-A1 Lubricating oil composition comprising an additive combination of a carboxylic acid and an amine as ant-rust agent SHELL OIL COMPANY 2004-10-28 US disclosed
US-6756346-B1 LOW ASH; ENVIRONMENTAL PROTECTION; PHOSPHOROTHIONATE, AMINE SALT OF PHOSPHORUS COMPOUND AND DITHIOPHOSPHATE ANTIWEAR AGENT; POLYALKYLENE POLYAMINE AND CARBOXYLIC ACID RUST PREVENTING AGENT SHELL OIL COMPANY 2004-06-29 US disclosed
US-20040053794-A1 Lubricating oil composition SHELL OIL COMPANY 2004-03-18 US disclosed
WO-2002079358-A2 LUBRICATING OIL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2002-10-10 WO disclosed
EP-1109882-B1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INT RESEARCH (NL) 2002-07-17 EP disclosed
EP-1109882-A1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2001-06-27 EP disclosed
WO-2000011122-A1 LUBRICATING OIL COMPOSITION USEFUL IN HYDRAULIC FLUIDS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2000-03-02 WO disclosed