Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.36 |
| ▸ | NQO2 | P16083 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422584 | 0.87 | ESR1 (0.55) | ESR1ESR2PTGS1NQO2PTGS2 | |
| SCHEMBL12657464 | 0.87 | ESR1 (0.41) | ESR1ESR2PTGS1NQO2PTGS2 | |
| SCHEMBL12657383 | 0.84 | ESR1 (0.39) | ESR1ESR2PTGS1NQO2PTGS2 | |
| SCHEMBL10104060 | 0.83 | ESR1 (0.38) | ESR1ESR2PTGS1NQO2PTGS2 | |
| SCHEMBL12657463 | 0.77 | CHAT (0.52) | KDM4EMAPTLMNAHDAC8APOBEC3A | |
| SCHEMBL13498157 | 0.75 | ADRA2A (0.44) | ESR1ESR2ADRA2AADRA2BADRA2C | |
| SCHEMBL12240373 | 0.74 | MAPT (0.42) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL14984198 | 0.73 | PTGS1 (0.59) | ESR1ESR2PTGS1NQO2PTGS2 | |
| SCHEMBL10104056 | 0.72 | ESR1 (0.36) | ESR1ESR2PTGS1NQO2PTGS2 | |
| SCHEMBL9247342 | 0.70 | ESR1 (0.50) | ESR1ESR2PTGS1NQO2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018847-B1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | ORÉAL L (FR) | 2014-09-17 | — | — | EP | disclosed |