Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104225 | 0.87 | ALDH1A1 (0.33) | RAB9ASMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL15624286 | 0.80 | MEN1 (0.40) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL16070411 | 0.72 | CHAT (0.30) | — | |
| SCHEMBL27860160 | 0.69 | ALDH1A1 (0.37) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL29121073 | 0.68 | CHAT (0.40) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL18774313 | 0.68 | MEN1 (0.33) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL16070323 | 0.68 | MAOA (0.30) | — | |
| SCHEMBL27891689 | 0.68 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| Bromide SCHEMBL29216854 | 0.67 | CHAT (0.39) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL16070317 | 0.67 | NPC1 (0.32) | NPC1RAB9ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018847-B1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | ORÉAL L (FR) | 2014-09-17 | — | — | EP | disclosed |